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Filtered Search Results
Selleck Chemical LLC AST-487
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AST-487 (NVP-AST487) a N N -diphenyl urea is an ATP competitive inhibitor of Flt3 with ki of 0 12 M Besides FLT3 AST487 also inhibits RET KDR c-KIT and c-ABL kinase with IC50 values below 1 M
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Selleck Chemical LLC Apabetalone
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Apabetalone (RVX-208 RVX-000222) is a potent BET bromodomain inhibitor with IC50 of 0 510 M for BD2 in a cell-free assay about 170-fold selectivity over BD1 Phase 2
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eMolecules 890129-26-7 | Medchem Express | BGG463 | 5mg | 446255802 | HY-100600 | 578.596 | C30H29F3N6O3
Medchem Express | BGG463 | 5mg | 446255802 | HY-100600 | 890129-26-7 | 578.596 | C30H29F3N6O3
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eMolecules 2369979-68-8 | Medchem Express | JHU37160 | 5mg | 596608116 | HY-131881 | 358.85 | C19H20ClFN4
Ambeed | (1R5S6r)-rel-3-Oxabicyclo[3.1.0]hexane-6-carboxylic acid | 250mg | 586027764 | A149405 | 55780-88-6 | MFCD19228486 | 128.127 | C6H8O3
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eMolecules 61281-37-6 | Medchem Express | Schisandrin B | 10mg | 446274590 | HY-N0089 | MFCD00210555 | 400.471 | C23H28O6
Medchem Express | Schisandrin B | 10mg | 446274590 | HY-N0089 | 61281-37-6 | MFCD00210555 | 400.471 | C23H28O6
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Medchemexpress LLC HY-112606 5mg Medchemexpress, ML-290 CAS:1482500-76-4 Purity:>98%
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Medchemexpress, HY-112606 5mg ML-290 CAS:1482500-76-4 ML-290 is a first-in-class and potent relaxin/insulin-like family peptide receptor ( RXFP1 ) agonist and activator of anti-fibrotic genes, with an EC 50 of 94 nM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112569 5mg Medchemexpress, MAT2A inhibitor 2 CAS:13299-99-5 Purity:>98%
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Medchemexpress, HY-112569 5mg MAT2A inhibitor 2 CAS:13299-99-5 MAT2A inhibitor 2 is a methionine adenosyltransferase 2A (MAT2A) inhibitor. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-112610 5mg Medchemexpress, CF53 CAS:1808160-52-2 Purity:>98%
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Medchemexpress, HY-112610 5mg CF53 CAS:1808160-52-2 CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a K i of <1 nM, K d of 2.2 nM and an IC 50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-108597 5mg Medchemexpress, TC-S 7005 CAS:1082739-92-1 Purity:>98%
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Medchemexpress, HY-108597 5mg TC-S 7005 CAS:1082739-92-1 TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC 50 s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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MEDCHEMEXPRESS LLC METAFLUMIZONE 100MG
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501872536 METAFLUMIZONE 100MG
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Accela Chembio Inc 3-ethoxy-4-(ethoxycarbonyl)phenylacetic Acid | 25g | 99469-99-5 | MFCD08704233 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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3-ethoxy-4-(ethoxycarbonyl)phenylacetic Acid | 25g | 99469-99-5 | MFCD08704233 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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MEDCHEMEXPRESS LLC ETOSALAMIDE 10MG
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501874295 ETOSALAMIDE 10MG
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![Medchemexpress LLC Benzoic acid, 4-[[[3,5-bis(1,1-dimethylethyl)phenyl]methyl][2-[[(4-chlorophenyl)methyl] | 1834571-82-2 | 99.9% | 751.20 | C37H36ClF5N2O5S | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236433.png-250.jpg)
Medchemexpress LLC Benzoic acid, 4-[[[3,5-bis(1,1-dimethylethyl)phenyl]methyl][2-[[(4-chlorophenyl)methyl] | 1834571-82-2 | 99.9% | 751.20 | C37H36ClF5N2O5S | 100MG
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AC-4-130 is a small-molecule inhibitor that targets the STAT5 SH2 domain to block STAT5 activation, dimerization, nuclear translocation, and STAT5-dependent transcription. It has demonstrated anti-cancer activity by inducing cell-cycle arrest and apoptosis in FLT3-ITD-driven leukemic cells and is provided for research use in biochemical and cell-based assays.
- Selective STAT5 SH2 domain inhibitor.
- Disrupts STAT5 activation, dimerization, and nuclear translocation.
- Induces cell-cycle arrest and apoptosis in FLT3-ITD leukemia models.
- High purity, 99.9% (HPLC).
- Molecular weight 751.20; formula C37H36ClF5N2O5S.
- Available as solid (5 mg-100 mg) and 10 mM solution in DMSO.
- Supplied with batch-specific certificate of analysis.
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Medchemexpress LLC 4-Phenoxybenzylamine | 107622-80-0 | 98.45% | 199.25 | 1 ML
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4-Phenoxybenzylamine inhibits the function of the NS3 protein by stabilizing an inactive conformation with an IC50 of about 500 μM against FL NS3/4a. It binds at an allosteric site located at the interface between the protease and helicase domains of the Hepatitis C Virus (HCV) NS3 protein, thus representing a new class of direct acting antiviral agents.
- Inhibits the function of the NS3 protein by stabilizing an inactive conformation.
- IC50 of about 500 μM against FL NS3/4a.
- Represents a new class of direct acting antiviral agents.
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![Medchemexpress LLC 2,4-Pyrimidinediamine, N2-[4-[(3-aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl) HCl | 2700435-52-3 | 99.5% | 400.91 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387884-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2,4-Pyrimidinediamine, N2-[4-[(3-aminopropyl)amino]phenyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl) HCl | 2700435-52-3 | 99.5% | 400.91 | 50 MG
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VEGFR-2-IN-5 hydrochloride is an off-white to light yellow solid. It is identified as a VEGFR2 inhibitor, extracted from patent WO2013055780A1. This compound targets VEGFR, demonstrating activity against VEGFR2.
- Acts as a VEGFR2 inhibitor.
- Appearance: off-white to light yellow solid.
- Complies with given specifications.
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